Halal Perspectives on Collagen-Based Biomaterials in Tissue Engineering Applications

Abstract

The halal status of biomedical applications has recently been under intense demand due to the utilization of critical ingredients in developing the products. One of the disciplines in biomedical applications, uses various types of biomaterials is tissue engineering. Due to its promising biocompatibility, low antigenicity, and biodegradability, collagen is well known and frequently employed as biomaterials for tissue engineering applications. Most of collagen come from sources including bovine, porcine, marine, and other mammal species. These huge sources end up being one of the most important factors in determining the halal status. Therefore, the purpose of this review is to emphasize collagen's application as biomaterials from the halal standpoint. Additionally, several collagen sources and their status as halal biomaterials for neural, skin, bone, and tissue engineering were covered, with an emphasis on the potential implementation of collagen from halal sources.